Weekly Chest CasesImaging Conference Cases

Case No : 4

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  • Age/Sex 69 / M
  • Case Title Nocardiosis
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Diagnosis With Brief Discussion

Lab
Pleural effusion analysis: Polymorphonuclear leukocytes dominant exudate
Culture (-), Fungus culture (-), AFB (-)
Leukocytosis and CRP (9.6 mg/dl)
Chief Complaint
Dyspnea, general weakness
Past History
DM, COPD
Reviewy
Nocardia
- Aerobic Gram-positive bacilli of with branching filament.
- Weakly acid fast
Common natural inhabitants of the soil
Rare among normal population, most infections occurring in immuno-compromised hosts.
Structural lung disease, pulmonary alveolar proteinosis (PAP), diabetes mellitus is also known risk factors.

Radiographic manifestations are pleomorphic
- Multifocal lung consolidation, nodules and masses
: Abscess formation, Cavitation (~1/3)
- Pleural Involvement
: Loculated pleural effusion and pleural thickening
- Chest Wall Extension, resulting empyema necessitatis

Differential diagnosis
Tuberculosis
- Mediastinal and hilar lymphadenopathy is not a usual feature of pulmonary nocardiosis
Actinomycosis
- Usually develops in patients with poor dentition
- Immunocompromised condition does not appear to be a risk factor of actinomycosis
Septic lung
Vasculitis
Malignancy
Keywords
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Current Editor : Sang Young Oh, M.D., Ph.D Email : sangyoung.oh@gmail.com

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